Deformulation Labs

Deformulation analysis of a product, also known as “chemical reverse engineering” is the process of analytically breaking down a material or product’s formulation to separate and determine the specific identity and exact quantity of both its major and minor constituent components.

When combined with product reformulation or formula re-engineering services, our skilled chemists can also redevelop the manufacturing production process (or “recipe”) instructions detailing how to recreate the original product. Avomeen has successfully reverse engineered and re-created hundreds of products and formulations using advanced extraction and analytical techniques to separate, identify, and quantify the ingredients/components.

Avomeen’s independent testing lab proudly serves entrepreneurs, manufacturers, distributors, lawyers, other laboratories & companies of all sizes

Avomeen’s deformulation services can be used to analyze and re-engineer a wide variety of consumer, industrial, and specialty products including:

  • Coatings
  • Cleaners
  • Chemicals
  • Polymers
  • Pharmaceuticals
  • Inks
  • Cosmetics
  • Supplements
  • Sunscreens
  • Household Products
  • Oils

 

Common reasons to analyze a product’s formulation using deformulation services:

  • Duplicate and recreate or improve upon an existing formulation. Obtain a product’s ingredients list, quantities of each ingredient, and its production process.
  • Identify and quantify all of the ingredients in a competing formulation gaining invaluable information such as which active ingredients make the competing product perform better, allow it to be produced at a lower cost, or allow the formulation to meet its various specifications.
  • Your product’s current manufacturer keeps raising their costs, the quality of the end products you’re being delivered is degrading over time, you’re stuck paying high fees due to having to import the product from overseas, or your current manufacturer is going out of business and you require the necessary information needed to develop the product yourself.
  • You believe that a competitor is infringing on your product’s patent or intellectual property, or your company is being sued and needs to prove that your formulation is not in violation.
  • In order to gain invaluable information for your marketing team on why your product performs better and/or safer than your competitor’s.  This instills confidence and trust in your brand turning potential customers into buyers.
  • You need a failure analysis performed to identify unknown ingredients or contaminants in your product in order to quickly rectify your product’s defect and prevent a costly recall. Our laboratory can detect and identify various constituents within a product at very small levels in order to identify trace impurities.
  • Identify any batch-to-batch irregularities or variations within your product through a Good-Vs-Bad sample analysis.  This ensures that your customers are getting an effective and safe product regardless of which lot the product came from.
  • Evaluate a new product or raw material supplier before you enter into a long term contract or complete industry/government regulatory testing stadards
  • Discover unsafe, obsolete, or banned ingredients/substances within a formulation so appropriate functional replacements can be swapped in allowing you to develop and sell your product in various international markets. This technique can also be utilized to create eco-friendly versions of existing formulations by exchanging questionable materials in a formulation with natural counterparts.
  • Confirmation of product identity during product development and for product benchmarking.
  • We can swap out ingredients in your product with more environmentally friendly raw materials.  We can also take products with hazardous concerns and reduce or eliminate the use of toxic ingredients.

Deformulation analysis and reformulation projects:

Deformulation services, in a way, are like analyzing and chemically breaking down a finished cake in order to discover how to recreate it. The initial deformulation process reveals the product’s raw ingredients and components such as eggs, salt, butter, sifted flour, etc. A complete deformulation even quantifies these identified components which can determine the exact amount needed for each item.

Then a reformulation analysis determines the process of how and when these ingredients are combined, what instruments and machinery are needed, and what conditions and technical methods are utilized. Essentially, reformulation services discover the “recipe” of how to make a product.  Once complete, this service shows the exact ingredients list, quantities utilized, and the production process which when combined can be used to recreate the original product that was analyzed.  It is also common during the reformulation stage to make specific modifications to ensure the new final product developed is a unique and innovative formulation, although still based off of the original formula.

Avomeen has successfully chemically reverse engineered and re-created hundreds of products and formulations. We use advanced extraction and analytical techniques to separate, identify, and quantify the ingredients/components within a wide range of both industrial & commercial products, as well as specialty goods. While many laboratories advertise services to identify a formulation’s major components, few can accurately deliver a complete deformulation analysis that identifies and quantifies the ingredients in a complex formulation. Even fewer can successfully re-combine the ingredients in order to deliver the formulation’s proper production process or “recipe”.


Avomeen is FDA-Registered & Inspected, DEA-Licensed, cGMP-Compliant, GLP-Compliant, ISO 17025-Accredited, and Reach/RoHS Compliant.

Contact us below for a consultation with one of our expert scientists or to request a quote

Call: 800-930-5450
Email: scientist@avomeen.com


Experience the Avomeen difference:

  • Quality Service – We pride ourselves on the level of customer service we give each client as each project receives a dedicated team of chemists to provide support both during and after the project is completed.
  • Ph.D. Consultation – We offer complementary initial consultations with our experienced chemists who can describe the process involved to complete the analysis, identify potential challenges, and quickly deliver you a customized proposal.
  • Strict Confidentiality – Our clients own all testing data produced and the results developed on their behalf.  Intellectual Property (IP) Rights to products are transferred to client
Ingredients a product de-formulation analysis can identify and quantify:

  • Major & Minor Components
  • Active & Inactive Ingredients
  • Matrix Resins & Polymer Resin Identity
  • Binders, Fillers, Dispersants, Synergists
  • Thermal & UV Stabilizers
  • Activators, Inhibitors
  • Antioxidants
  • Flame Retardants
  • Wetting Agents
  • Pigments, Additives, & Trace Ingredients
  • Impact Modifiers, Reinforcing Fibers, & Extenders
  • Functional Groups Analysis
  • Inorganic & Organic Materials
  • And More!

Reformulation Services:

Clients often times ask us to modify or improve upon a product’s formulation while recreating it.  When reformulating or recreating a product for you Avomeen’s chemists will send you trial batches (Iterations/Prototypes) during the development process for you to evaluate and critique on. Once your new formulation meets your exact specifications we can then perform a technology transfer allowing you to produce the product yourself in-house or bring it to the contract manufacturer of your choice. If you need a suitable contract blender or manufacturing expertise, our experienced teams of chemists maintain many contacts within the industry and can help you find a suitable home for your product.

Questions we often receive on our deformulation services:

  • Full Identification & Quantitation of All Components
  • Semi-Quantitative Identification of Major and Minor Ingredients (Chemical Class & Function)
  • Identification of Major Components
  • Quantification of Specific Components
  • Full Deformulation & Reformulation (Duplication/Re-Engineering)
  • Partial Deformation & Reformation (New Product Innovation Based on Existing Technology)
  • Source Materials and Suggest Alternative Ingredients
  • Q1 & Q2 Testing & Regulatory Submissions (Pharma)
  • Pigments, Dyes, & Inks
  • Pharmaceuticals & Drug Delivery Systems
  • Nutraceuticals (Supplements, Vitamins, Multi-Vitamins)
  • Medical Devices & Similar Products
  • Paints & Coatings (Liquid, Powder, Inks, Toner, Architectural, Automotive, Stains, Finishes, Etc.)
  • Sheets, Films, Multi-Layer Films, & Coatings on Films
  • Polymers, Plastics, & Residual Monomer Levels & Molecular Weight (Plasticizers, Pellets, PET, PMMA, Degradable Products, PP, PU, SAN, Nylon, PE, Flexible & Rigid PVC)
  • Copolymers, Blends/Mixtures & Multilayer Architectures
  • Additives (PSA, Hot Melts, Water Borne)
  • Adhesives & Sealants (Epoxy, Silicone, PU)
  • Aerospace & Automotive
  • Cleaners & Cleaning Solutions (Industrial & Commercial, Detergents, Surface Cleaning Agents, Pool Treatments)
  • Soaps (Facial, Hand, Anti-Bacterial, Etc.)
  • Rubber & Latexes (TPE, EPDM, Neoprene, Natural, SIS, EVA, PUR, NBR, Silicone, Etc.)
  • Beverages (Soft Drinks, Energy Drinks, Vodka, & other Liquors)
  • Composites, Fibers, & Textiles (Carob, Graphite, Kevlar Fibers, Garment, Upholstery, Etc.)
  • Manufactured Goods, Process Solutions, & Fabricated Parts
  • Lubricants (Commercial & Industrial)
  • Solvent Mixtures & Surfactant-Based Products or Mixtures
  • Home, Health, & Beauty Products
  • Cosmetics (Shampoos, Conditioners, Creams, Gels, Ointments, Powders, & Feminine Products)
  • Car Care Products (Waxes, Soaps, Creams, Sprays)
  • Packaging Materials
  • Decomposition products
  • Automotive Parts (Metals, Polymers, Coatings, Cleaners, Etc.)
  • Spa Treatments (Sun-Tanning & Bronzing Lotions)
  • E-Liquid / E-Cigarette Formulations
  • Wastewater & Water Treatment Chemicals
  • Waste Streams
  • Metals & Electrical Components
  • Unknown Materials & Substances
  • Fourier Transform Infrared Spectroscopy (FTIR)
  • Gas Chromatography / Mass Spectroscopy (GC/MS)
  • Liquid Chromatography / Mass Spectroscopy (LC/MS)
  • Ion Chromatography (IC)
  • Nuclear Magnetic Resonance Spectroscopy (NMR)
  • Gas Chromatography / Flame Ionization Detection (GC/FID)
  • Thermogravimetric Analysis (TGA)
  • Thin Layer Chromatography (TLC)
  • Scanning Electron Microscopy / Energy Dispersive Spectroscopy (SEM/EDS)
  • Gel Permeation Chromatography (GPC)
  • Atomic Absorption Spectroscopy (AAS)
  • High-Performance Liquid Chromatography (HPLC)
  • Gas Chromatography-Mass Spectrometry (GC/MS)
  • SVOC Analysis
  • Ultraviolet / Visible Spectroscopy (UV/VIS)
  • Inductively Coupled Plasma (ICP)
  • X-Ray Diffraction (XRD)
  • Elemental Analysis
  • Rotary Evaporator Concentration
  • Soxhlet Extraction
  • Distillation
  • And More
  • Manufacturing and R&D Firms
  • Pharma Researchers & Manufacturers
  • Product Distributors
  • Patent Law Firms
  • Insurance Firms
  • Environmental Consultants
  • Other Laboratories
  • Entrepreneurs
We can perform a patent search to ensure that there are no patents that would prevent you from producing the product and entering the market. We have partnerships with IP law firms to ensure compliance with the laws and regulations.We can perform a patent search to ensure that there are no patents that would prevent you from producing the product and entering the market. We have partnerships with IP law firms to ensure compliance with the laws and regulations.
We do not! We value the privacy of each of our clients! All testing data and results produced through work on behalf of our clients is owned by our clients. We also offer a non-disclosure/confidentiality agreement which can be found at www.avomeen.com/NDA

Our clients use deformulation analysis for a variety of reasons, contact Avomeen today at (800) 930-5450 for consultation with one of our talented chemists who can help you solve even your most complex analytical or product development challenges.